Sex difference in sensitivity to allopregnanolone neuroprotection in mice correlates with effect on spontaneous inhibitory post synaptic currents
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چکیده
منابع مشابه
effects of low frequency stimulation on spontaneous inhibitory and excitatory post-synaptic currents in hippocampal ca1 pyramidal cells of kindled rats
objective: low-frequency stimulation (lfs) exerts suppressive effects in kindled animals. it is believed that overstimulated glutamatergic and decreased gabaergic transmission have long been associated with seizure activity. in this study, we investigated the effect of electrical lfs on different parameters of spontaneous excitatory and inhibitory post-synaptic currents (sepscs and sipscs) in h...
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چکیده ندارد.
15 صفحه اولCharacterization of spontaneous inhibitory synaptic currents in salamander retinal ganglion cells.
Spontaneous and light-evoked postsynaptic currents (sPSCs and lePSCs, respectively) in retinal ganglion cells of the larval tiger salamander were recorded under voltage-clamp conditions from living retinal slices. The focus of this study is to characterize the spontaneous inhibitory PSCs (sIPSCs) and their contribution to the light-evoked inhibitory PSCs (leIPSCs) in ON-OFF ganglion cells. sIPS...
متن کاملSpontaneous Inhibitory Synaptic Currents Mediated by a G Protein-Coupled Receptor
G protein-coupled receptors (GPCRs) affect many physiological processes by modulating both intrinsic membrane conductances and synaptic transmission. This study describes spontaneous miniature inhibitory postsynaptic currents mediated by vesicular dopamine release acting locally on metabotropic D2 receptors leading to the activation of a G protein-coupled inwardly rectifying potassium conductan...
متن کاملEffects of Low Frequency Stimulation on Spontaneous Inhibitory and Excitatory Post-Synaptic Currents in Hippocampal CA1 Pyramidal Cells of Kindled Rats
OBJECTIVE Low-frequency stimulation (LFS) exerts suppressive effects in kindled animals. It is believed that overstimulated glutamatergic and decreased GABAergic transmission have long been associated with seizure activity. In this study, we investigated the effect of electrical LFS on different parameters of spontaneous excitatory and inhibitory post-synaptic currents (sEPSCs and sIPSCs) in hi...
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ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2011
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2011.05.017